Arithmetic and Geometric Sequences in Hospital Drug Dosage Calculations

Overview of Drug Dosage Sequences in Hospital

This summary explains how arithmetic and geometric sequences are used to model drug dosages administered to patients in a hospital setting, using two examples: Kiri and Ted.


Kiri's Drug Dosage: Arithmetic Sequence

Kiri receives an increasing amount of a drug each day, starting with 1 mg on her first day. The daily increase is constant, making this an arithmetic sequence.

Key Information:

  • First day dosage (u1): 9 mg (calculated)
  • Daily increase (d): 2 mg
  • Dosage on 7th day (u7): 21 mg
  • Dosage on 11th day (u11): 29 mg

Formulas and Calculations:

  • General term: un = u1 + (n - 1)d
  • For 7th day: u7 = u1 + 6d
  • For 11th day: u11 = u1 + 10d

Solving for u1 and d:

  1. Subtract equations: u11 - u7 = 4d
  2. Substitute values: 29 - 21 = 4d → 8 = 4d → d = 2
  3. Substitute d back: 21 = u1 + 6(2) → u1 = 9

Total Dosage Over 30 Days:

  • Use sum formula: Sn = n/2 × [2u1 + (n - 1)d]
  • S30 = 30/2 × [2(9) + 29(2)] = 1140 mg

Ted's Drug Dosage: Geometric Sequence

Ted receives a drug dosage that decreases by 40% daily, starting at 20 mg on the first day. This forms a geometric sequence.

Key Information:

  • First day dosage (u1): 20 mg
  • Common ratio (r): 0.6 (since dosage decreases by 40%)

Calculations:

  • Dosage on 5th day: u5 = u1 × r4 = 20 × 0.64 = 2.592 mg

Finding When Dosage Falls Below 0.06 mg:

  • Inequality: u_k < 0.06 → 20 × 0.6^(k-1) < 0.06
  • Using solver, k ≈ 13 (first day dosage is less than 0.06 mg on day 13)

Total Dosage Over First 13 Days:

  • Sum of geometric series: S_k = u1 × (1 - r^k) / (1 - r)
  • S13 = 20 × (1 - 0.613) / (1 - 0.6) ≈ 49.9 mg

Summary

  • Kiri's dosage increases linearly by 2 mg daily, starting at 9 mg, totaling 1140 mg over 30 days.
  • Ted's dosage decreases by 40% daily, starting at 20 mg, falling below 0.06 mg on day 13, with a total of approximately 49.9 mg over 13 days.

These examples demonstrate practical applications of arithmetic and geometric sequences in medical dosage planning, highlighting how to calculate individual dosages, total amounts, and critical thresholds.

For a deeper understanding of the mathematical principles involved, check out Understanding Arithmetic and Geometric Sequences with Summation Examples and Calculating Profits Using Arithmetic and Geometric Sequences. Additionally, if you're interested in mastering the concepts of sequences and series, visit Mastering Sequence and Series: A Comprehensive Guide.

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